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Cleoflora™ Vaginal & Gut Synbiotic

Rated 4.8/5  - Based on 7,832+ Reviews

The first clinically-backed scoopable synbiotic—combining our 3 in 1, pre-, pro-, and postbiotics to support your vaginal, gut, and urinary health for effortless freshness and confidence.

Selling Fast: 198 Sold in the past 24 hours!

Helps break the cycle of odor & flare-ups — so you can finally feel fresh and confident again.

Balances pH — for vaginal comfort and worry free intimacy

Supports gut, vaginal & urinary harmony — for balance, regularity, and ease of bloating

$1.16 Per Serving!

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1 Bag=30 Day Supply

60 Day Guarantee

Is This For You?

  • If you check any of these boxes, then Cleoflora is a no-brainer:

    You've noticed unusual discharge, odor, or itch — and you're done guessing why

    You're actively intimate and want to feel confident, not anxious

    You've tried other probiotics, antibiotics, or boric acid — and nothing stuck

    You want one solution for vaginal, gut, and urinary health — not five different products

Recommend Usage

Gently stir the mix with 8oz of water, take one serving daily. Do not mix with hot liquids to keep the probiotics active.

 

A Gentle Start for Your System
To slowly introduce your body to the probiotic blend:
Days 1–3: Take ½ scoop once daily
Days 4–7: Increase to ¾ scoop
Day 8+: Move to the full 1 scoop daily

 

This gradual approach helps your body adjust naturally and comfortably.

Keep the bag in a cool, dry place.

 

Consistency is key—Cleoflora is fully effective around 8 weeks in.

 

Ingredient Facts

Serving Size: 2g scoop, 30 servings per container (30 day supply). 
CleoBalance Synbiotic Blend, 150mg: Lactobacillus rhamnosus, Lactobacillus reuteri, Lactobacillus acidophilus, Lactobacillus crispatus, Lactobacillus gasseri, Lactobacillus jensenii, Bifidobacterium lactis, Bifidobacterium longum subsp. infantis, Lactobacillus plantarum

 

Other Ingredients: Galacto-oligosaccharides (GOS), Tribuytrin, Pullulan, Sunflower lecithin, Citric Acid, Raspberry Natural flavor, Lemon Natural Flavor, Stevioside, Xylitol, Erythritol

Research Backed Ingredients Featured In:

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'Fresh Start Bundle!'

Jump start your freshness journey — it's completely FREE! Designed to make consistency easy, enjoyable, and effective!

This Is Total Feminine Balance. 
Not Another Probiotic. 

Clinically studied, OB-GYN-trusted strains — thoughtfully formulated to support your entire feminine system and actually survive the journey.

 

The Formula That Understand Women

Cleoflora's CleoBalance™ Synbiotic Blend delivers 22.5 billion CFUs and 9 targeted strains at clinical strength—not "at time of manufacture." At the time you take it. So you're never guessing if it's working.

Vaginal, Gut, & Urinary Tract Support

Your vaginal microbiome is connected to your gut—when one is off, the other can't stabilize. Cleoflora's TriBio Sequence™ supports all three systems together with prebiotics, probiotics, and postbiotics—helping reduce flare-ups after sex, periods, or stress. So balance feels steady, not temporary.

Designed to Reach Where It Matters 

Most probiotics die before they reach you—during shipping, on the shelf, in your stomach acid, before they even reach your vaginal tract. Cleoflora's Pullulan Survival Matrix™ shields each strain individually from moisture, heat, and digestive acid. They're alive when you take them. Alive when they reach your gut. Real bacteria, delivered where they matter, effortless freshness and confidence...

With Every Scoop You Get Ingredients
 That Work With Your Body's Natural Processes

Made in a cGMP-certified facility & 3rd party tested for potency and purity

100% Natural

Non-GMO

Vegan Friendly

Gluten Free

100% Natural

Non-GMO

Vegan Friendly

Gluten Free

With Every Scoop, You Get Ingredients
 That Work With Your Body's Natural Processes.

Made in a cGMP-certified facility & 3rd party tested for potency and purity

Free From Common Irritants

No sugar, dairy, soy, or gluten — and no artificial fillers or dyes.

Clinically Guided Ingredients

Formulated with clinically studied strains and guided by OB-GYN expertise.

Clean, Vegan & Non-GMO

Ethically sourced, plant-based ingredients you can feel confident using daily.

Delayed Release Delivery

Engineered to protect strains through digestion for effective delivery.

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Quality You Can Trust in Every Scoop

Manufactured and handled according to international safety and quality standards, with routine screening that includes:

Tested for Heavy Metals  

Screened For Microbial Contaminants

Screen For Ingredient Purity

100% Natural

Non-GMO

Vegan Friendly

Gluten Free

Over 89,000 Women Have Found Lasting Freshness

The Science Behind Cleoflora Synbiotic

  •  The Vaginal Microbiome

  •  Vagina-Gut Connection

  •  The Cleoflora Difference

 

The vagina has a naturally diverse balance of bacteria. Without enough Lactobacillus probiotics, its pH can become unbalanced, allowing bad bacteria to thrive, which can cause odor and discomfort.

 

 

Your gut and vaginal health are more connected than you think. When your gut is low on beneficial strains like Bifidobacterium and Lactobacillus, it can cause bloating, irregularity, and may even throw off your vaginal balance, too.

Most probiotics only work on your vagina. Cleoflora works on your gut, vagina, and urinary tract at the same time by filling them with the right good bacteria. This gets rid of odor where it starts, not just covers it up. 

 

With 22.5 Billion good bacteria, plus prebiotics (food for the good bacteria) and postbiotics (helpers that keep things balanced), you get lasting freshness, healthy pH, less bloating, and easy daily bathroom trips—naturally.

Formulated with guidance from board-certified OB/GYNs who specialize in vaginal health.

Trusted by Experts. Made for You.

“Most vaginal probiotics fail for two reasons.


First, many strains never survive digestion. And even when they do, they’re often delivered alone — without the prebiotics and postbiotics needed to help them actually colonize and thrive.

 

Cleoflora addresses both problems.
It uses clinically relevant strains — L. crispatus, L. rhamnosus, and L. reuteri — and supports them with a full synbiotic system designed for real, lasting balance.

 

This formula reflects how vaginal and gut health actually work — not how most probiotics are marketed.”

Dr. Kelsey Desantis

MD, FACOG | Board-Certified OB/GYN

“When we formulated Cleoflora, we weren’t trying to follow trends — we were trying to build something women could feel safe trusting.

 

Every strain we use is well-studied and chosen for a reason, with doses aligned to published research — not inflated numbers.

 

We also developed our Pullulan Survival Matrix™ to help protect those strains from moisture and digestion, so they can arrive supported and alive — not broken down before they have a chance to work.

 

This is what evidence-based women’s health looks like when it’s built with care.”

Dr. Kristina Stewart

MD | Chief Medical Officer, Cleoflora

Clinically Studied. Clinically Effective.

90%

90% of women restored a healthy vaginal microbiome in 21 days using a Lactobacillus synbiotic.

88%

Of women cleared bacterial vaginosis with Lactobacillus rhamnosus probiotic.

92%

Of women taking our Lactobacillus rhamnosus GR-1 and reuteri RC-14 maintained a healthy vaginal pH.

85+

Cleoflora’s included probiotic strains have been evaluated in over 85 clinical trials in women’s health, digestion, and immune support.

Backed by Science: View Ingredients

The Cleoflora™ Difference

The only synbiotic built for the entire feminine system — with targeted strains and real survivability other probiotics can’t match, so you can finally feel fresh, confident, and in control again.

Cleoflora Synbiotic

Other Brands

Balances Vaginal pH & Odor at the Source

Powered by CleoBalance™ Synbiotic Blend

Doesn't target the source of imbalance

Strains That Survive Digestion

Protected by Pullulan Survival Matrix™ 

Strains die before reaching the microbiome

Targets the Entire Feminine System

Supports your vaginal, gut, & urinary tract for lasting freshness

Only "supports" your vaginal microbiome

Clinically Relevant Strain Count

22.5B CFUs from 9 feminine-focused strains

Low strain count or irrelevant strains

Delicious Daily Flavor

Makes a daily habit easy!

Bitter, chalky aftertaste

Got Questions?
We've Got You.

Why is Cleoflora priced higher — and what makes it more effective?

Cleoflora isn’t “just another probiotic.” It’s the first scoopable vaginal-focused formula built for women who’ve tried everything and still feel stuck in the cycle of odor, imbalance, and recurring infections.

 

Most probiotics are generic probiotic pills. Cleoflora was created differently — designed for your entire feminine microbiome:

 

9 clinically studied strainsthe most comprehensive lineup available.
Each strain was chosen for its specific role in feminine balance, including L. crispatus, L. rhamnosus, and L. reuteri — some of the most studied and most effective probiotics for supporting healthy vaginal flora, reducing odor, and helping restore long-term balance.


It’s one of the only formulas that uses the exact strains women’s health research has consistently validated.

 

CleoBalance™ Synbiotic Blend — our prebiotic + probiotic + postbiotic trio that works together so good bacteria don’t just enter your body… they thrive, rebuild, and stabilize your natural defenses.

 

FloraPreserve™ Pullulan Matrix — a gentle protective layer that keeps our probiotics alive through water, heat, moisture, and digestion so more reach your gut–vagina axis intact, making it the most effective delivery method possible.

 

3-in-1 Feminine Health Support
Cleoflora works across the gut–vagina–urinary tract axis, supporting all three systems at once for more complete, predictable balance.

 

First-of-its-kind scoopable format — no fillers, no giant capsules, no half-dead strains. Just a concentrated, protected, high-quality powder made to actually work.

In short:
every part of Cleoflora — from the clinical strains to the protective matrix to the complete synbiotic system — is significantly more expensive to produce than standard probiotic capsules.

 

This is why Cleoflora sits at a higher price point:

you’re paying for potency, survival, and results, not the watered-down blends that failed you before.

 

It’s not priced like “another probiotic” because it isn’t one.


It’s a new category — made to finally work when nothing else has.

How does Cleoflora ensure safety and quality?

Cleoflora is formulated to support balance, not disrupt it. We use clinically studied, OB-GYN–friendly probiotic strains that have been researched for helping reduce the recurrence of BV, yeast, and UTIs — not contribute to them.

 

Our Safety Standards:
Clinically studied ingredients
OB-GYN–friendly formula
Made in a cGMP-certified, FDA-registered facility
Third-party tested for purity, strength, identity, and composition
Regulated under FDA dietary supplement guidelines

 

At Cleoflora, we follow the FDA’s “current Good Manufacturing Practice” (cGMP) regulations, which require rigorous testing and strict quality controls. While the FDA doesn’t “approve” dietary supplements, they do regulate how they’re made — and we meet every standard.

Will Cleoflora cause  any irritation or discomfort like other treatments?

Cleoflora is made with clinically studied ingredients that are gentle yet effective , it works with your body's natural processes— and because it’s taken orally, it already eliminates the burning, stinging, and irritation women often experience with gels, suppositories, and acids.

If you’re still concerned about sensitivity, or are new to probiotics, you can follow a simple acclimation routine to ease your body in:

 

A Gentle Start for Your System
To slowly introduce your body to the probiotic blend:
Days 1–3: Take ½ scoop once daily
Days 4–7: Increase to ¾ scoop
Day 8+: Move to the full 1 scoop daily

 

This slow-start method helps your gut and vaginal microbiome adjust comfortably, especially if you’re new to probiotics or have had reactions to other products before.

Will Cleoflora mess up my cycle, hormones, fertility, or pregnancy?

No — probiotics do not alter your hormones or cycle. Cleoflora simply supports the microbiome, which is separate from hormone regulation. Many women take probiotics throughout TTC, pregnancy, and postpartum — but we still recommend checking with your provider if you’re currently pregnant just for personal peace of mind.

Does a scoop this small even do anything?

Yes — because potency isn’t about size. Cleoflora contains 22 billion CFU across 9 targeted strains plus pre- and postbiotics. Powder allows for precision dosing without fillers or oversized capsules. That tiny scoop is concentrated, protected, and proven — not watered down.

How do I take Cleoflora Synbiotic?

Just mix one scoop a day into 8-10oz of water and drink — morning or night, whatever fits your routine.

You can take it on an empty or full stomach.


Most women tolerate it perfectly either way, but if you’re more sensitive to probiotics, taking it with food can make the adjustment even gentler.

A Gentle Start for Your System
To slowly introduce your body to the probiotic blend:
Days 1–3: Take ½ scoop once daily
Days 4–7: Increase to ¾ scoop
Day 8+: Move to the full 1 scoop daily

 

And as with any supplement, feel free to check with your healthcare professional if you have specific questions about your needs or routine.

Is it normal to have minor bloating or extra gas at first?

Yes — a small adjustment phase is common with any probiotic. It’s simply your microbiome waking up and shifting toward balance. It’s temporary, usually mild, and typically fades within a few days as the good bacteria take hold.

Can this give me a UTI, yeast infection, or ureaplasma?

Cleoflora is designed to support balance, not disrupt it. The probiotic strains we use have been clinically studied for helping reduce the recurrence of BV, yeast, and UTIs, and because it’s taken orally, nothing is inserted vaginally — so there’s no added risk of introducing outside bacteria or upsetting delicate tissue.

 

While everyone’s body is unique, Cleoflora is formulated to work with your natural microbiome, making it a gentle, low-risk option for most women looking to restore a healthy balance.

How long does it take for Cleoflora to work?

Cleoflora isn’t a band-aid fix — it’s an inside-out reset that gradually transforms your flora so you can finally feel normal again. It’s not a sprint; it’s a gentle return to a body you trust.

3 days:
A lighter, fresher feeling that makes you think, “Okay… something’s changing.”

 

7 days:
Odor becomes less noticeable, and the constant checking eases. You start feeling more in control.

 

1 month:
Your whole cycle feels more predictable. Freshness lasts longer, and intimacy feels less stressful and more comfortable.

 

6 weeks:
That “I feel normal again” moment. Your good bacteria are strong enough that you’re no longer bracing for flare-ups.

 

2 months+:
For many women, this is where it really clicks — no recurrences, no surprises, and a steady confidence that lasts day to day. You move through your cycle without second-guessing your body.

 

CleoBalance™ Synbiotic Blend + FloraPreserve™ Pullulan Matrix work together to support a gentle, steady transformation — not an overnight fix, but a lasting one.

Synbiotic? Probiotic? CFUs? What does it all mean?

Probiotics
The good bacteria your body needs to stay balanced and odor-free — especially Lactobacillus strains that keep your pH healthy.

 

Prebiotics
The “food” that helps those good bacteria grow stronger and last longer.

 

Postbiotics
The beneficial compounds good bacteria naturally produce to support gut and vaginal health.

 

Synbiotic
All three working together.
Our CleoBalance™ Synbiotic Blend combines pre + pro + postbiotics for a more complete, inside-out approach to feminine balance.

CFUs

A count of how many live probiotics you’re getting.

Cleoflora delivers 22 billion CFUs for meaningful, clinically supported results.

 

Pullulan
Our FloraPreserve™ Pullulan Matrix gently protects the probiotics so they stay alive through water, moisture, heat, and digestion.

Join the Freshness Movement: See Why Women Love Cleoflora!

From Quiet Worry to Fresh Confidence — Here’s Why Thousands of Women Are Switching to Cleoflora

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Customers say

AI-generated from customer reviews

Customers report that Cleoflora works almost immediately, helping them feel fresh all day while effectively balancing pH and eliminating odor. Several women note they haven’t experienced recurring infections, with one describing it as a gentle reset. Along with vaginal health benefits, customers were surprised to find it also helped reduce bloating and support more regular digestion. The drink is described as subtly refreshing, and some users say they were impressed by the probiotic content. Opinions on value are mixed, with some finding it pricey, though many say it felt worth it compared to doctor visits, ineffective probiotics, and for the confidence and peace of mind it provided. Some were surprised by the small package size, but most found it effective.

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Customer Reviews

Based on 3146 reviews
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Angela S.

Every time I bent down, I used to smell myself. Thats gone. I had a mild reaction at first(im sensitive), but it smoothed out after a few days. Will absolutely keep this in my routine. In LOVE, 11/10!

J
Joanna M.

This actually improved how I feel *and* taste. Like, wow. Smelling like pineapple? Its real. Not overpowering just fresh. If youve tried everything else & nothing worked, seriously try this.

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Angie M.

The odor I thought would never go away? Gone within days. My discharge doesnt smell anymore, and I feel cleaner all day. If youve tried everything else to no avail, seriously try this.

A
Amber W.

This actually improved how I feel! Like, wow. The sweet scent is real. Not overpowering just fresh. A little scoop changed a lot for me.

R
Rebecca H.

Smelling sweet wasnt even the goalbut its the bonus I got. I was nervous about discomfort, but I havent had a single cramp since. No regrets. Just results. I cannot recommend enough!!

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. The views and nutritional advice expressed by Cleoflora are not intended to be a substitute for conventional medical service. Individual results may vary.

Cleoflora™ Vaginal & Gut Synbiotic

$69.00

✨ 50% Off — Just $1.16 Per Serving!

Cleoflora™ Vaginal & Gut Synbiotic

$69.00

✨ 2nd Month Free, Just $1.16 Per Serving!